"Menopause The Musical 2: Cruising Through 'The Change'® is a sequel to the original show, "Menopause The Musical." It follows the same four characters as they embark on a cruise, encountering new adventures, romances, and the challenges of the menopause while celebrating their enduring friendship.

The sequel picks up five years after the original, with the four friends taking a cruise together. They navigate the joys and trials of the menopause, including hot flashes, mood swings, and memory lapses, while also dealing with new relationships, grandchildren, and other life events.